← See the science · Yeast beta-glucan (1,3/1,6)

Buy Yeast beta-glucan (1,3/1,6)

Products that match the form and dose used in the studies. Umbral earns a commission on some purchases; the order never changes because of it.

Emerging

250 mg/day of insoluble yeast beta-glucan, taken continuously. The marathon trial dosed for 45 days before the event and 45 days after.

Ratings, prices and photos were read from Amazon on Sep 18, 2026. Amazon prices change; the current one is on the product page.

As an Amazon Associate, Umbral earns from qualifying purchases. Product data is provided by Amazon and may change; ratings and prices shown are Amazon’s, not Umbral’s. Recommendations are based on the evidence grade and the form used in trials, never on commission.

Nutricost Beta Glucan 500 mg 1,3/1,6 D-Glucan, 60 Vegetarian Capsules

4.6(361)

$16.95

Baker's yeast beta-1,3/1,6-glucan, which is the molecule with the immune data. Oat and barley beta-glucan is a different compound sold for cholesterol — it will not do this job.

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Amazon price on Sep 18, 2026.

NOW Supplements Beta-Glucans with ImmunEnhancer

4.6(1,627)

$15.30

The best-reviewed of the three. Look for the insoluble, particulate form specifically — in the head-to-head trial the soluble version did nothing.

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Amazon price on Sep 18, 2026.

Zazzee Extra Strength 1,3/1,6 Beta Glucans, 1000 mg

4.4(391)

$27.97

A higher-dose option if you want to run above the 250 mg/day used in the Wellmune trials.

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Amazon price on Sep 18, 2026.

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What to look for

✓Insoluble, particulate baker's yeast (Saccharomyces cerevisiae) beta-1,3/1,6-glucan — Wellmune WGP style. Buy the insoluble form specifically: the head-to-head trial found the soluble version did nothing. Not oat or barley beta-glucan, which is a different molecule for cholesterol.
✓250 mg/day of insoluble yeast beta-glucan, taken continuously. The marathon trial dosed for 45 days before the event and 45 days after.
✓Third-party tested (USP, NSF, Informed Sport)

What to avoid

✕Proprietary blends that hide the dose per ingredient
✕Unstandardised extracts with no active-compound percentage

Safety notes

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As an Amazon Associate, Umbral earns from qualifying purchases. Product data comes from Amazon and may change; ratings and prices are Amazon's, not Umbral's. Suggestions are based on the science and the form used in studies, never on commission.

Umbral is a wellness product, not a medical device. It does not diagnose, treat, cure or prevent any disease. Supplement information is educational; talk to a clinician before starting anything, especially if you are pregnant, under 18, managing a condition or taking medication.

These statements have not been evaluated by the Food and Drug Administration.